The New Frontier of Drug Design: NMR Spectroscopy on Living Cells Targets Ion Channels
Ion channels, the gatekeepers of the cell, are arguably some of the most critical proteins in human biology. Embedded within the fatty membrane of nearly every cell, these intricate protein assemblies regulate the flow of charged ions—such as sodium, potassium, calcium, and chloride—into and out of the cell. This seemingly simple regulatory function is the foundation for virtually all essential…
How Optical Genome Mapping is Revolutionizing Diagnosis for Recurrent Pregnancy Loss
Pregnancy loss is a devastating, common occurrence, affecting up to a quarter of all pregnancies. While most losses are isolated events, when a woman experiences three or more consecutive clinical pregnancy losses before 20 weeks gestation, it is medically classified as Recurrent Pregnancy Loss (RPL). RPL is a complex, heartbreaking condition that impacts 1% to 3% of couples trying to…
Psilocin Dampens Brain Activity in Mice, Offering Hope for AUD
Alcohol Use Disorder (AUD), a chronic and relapsing brain disease, affects millions globally and represents a severe public health crisis. Despite decades of research, current pharmacological treatments for AUD are often met with limited success, high relapse rates, and debilitating side effects. The core challenge in treating AUD lies in its complex interplay with emotional states: heavy alcohol consumption over…
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